Since the latest patch, the game has been crashing every 5 minutes for me (On PC). It's unbearable, near enough every time I fast travel or enter a new cell it crashes. It wasn't even this bad last time I played it back in November. The worst thing is, I can't even rollback the update because its all automated through Steam.
I know what you mean, it's not quite every 5 minutes but for me after a certain amount of time has elapsed it's usually going from inside to outside locations and it'll crash pretty much gauranteed. So I have to quick save every time before I go outside. It was never that bad before the latest update, and using the same mods. And that's another problem with Steams automatic updates, you can't pick and choose the ones you want if you have problems with the latest. Not a fan of that.
To be honest, after I've bought and finished LR to finish the story I'm done with New Vegas for good. Then it's hello Skyrim.
No need to be careful what you wish for, you probably won't get it.